Comparing Oral and IV Iron Supplementation Therapies

Completion and submission of the 48 hour task report according to the specified format will be required for a ‘satisfactory’ performance in the Medicine attachment.

Format for 48 hour task reports.

1.      Reports should be no more than 1000 words (excluding references)

2.      The report should be set out under the following headings:

         (a) Clinical question

         (b) Structure of literature search

         (c) Results of literature search

         (d) Assessment of relevant evidence identified from the literature search

         (e) Applicability of the evidence to the patient

3.      To be satisfactory, the report needs to be submitted on time, in the specified


Structure of the literature search:  this should present an outline of the databases searched and all the search terms used. Depending on the topic, it should include disease terms, study design terms, and specific author names for areas where specific researchers/authors are known to have undertaken relevant work. The student should include a short comment explaining the rationale for the search terms. Absence without explanation or justification of a search term or group of terms judged relevant by the assessor will cause the mark to be downgraded. There should be a brief consideration of any likelihood that the searches might have missed relevant papers

Results of the search: This section should summarise citation numbers returned by the initial searches, refinements made to the searches to ensure relevant citation returns, citations included and excluded, and finally, a list of citations judged relevant along with the basis for this. Failure to present to the assessor a clear ‘track’ through the search will cause the mark to be downgraded.

Assessment of relevant evidence: This should outline citations judged relevant to the question, explanation of why relevant, a measure of the level of the evidence and an appropriate critical appraisal (allowing for the timeframe of the 48 hour task) of the quality of individual studies/reviews/meta-analyses judged relevant to the question. In cases where searches returned little evidence, there should be discussion of why this might be the case. There should be a summary of the evidence and an opinion from the student on the strength of the evidence in relation to the question asked.

Applicability to the patient: A short consideration should be given of why the evidence applies or might not apply to the particular patient seen in the long case, what the benefits and drawbacks, set in the context of the patient’s circumstances, might be in applying the evidence to his/her specific case.

I’d be happy for you to do a 1000-word piece to fulfill items 2(b)-(d).


To discuss evidence and comparison between oral and iv therapy in the context of acute and also chronic settings.

Structure of Literature Search

            The study concerning the comparison of the use of IV and oral iron supplementation techniques utilized various sources from several databases to generate information. One of the databases was the PubMed Central (PMC) that has numerous archived research works of life and biomedical sciences in the form of journal articles. The database provided access to invaluable texts regarding the differences between IV and oral methods of supplementing iron for both chronic and acute cases. The other was the Cochrane databases that presented up-to-date details concerning the supplement therapies. Third, the WHO global database dealing with anemia also gave a platform from which critical information about the subject was obtained. The fourth database used to search for evidence was the EMBASE, that contained various journals in pharmacology, clinical medicine, medical devices, and drugs.

            The research entailed writing search terms in the databases to access the articles that provided details regarding IV and oral techniques of iron supplementation. The concepts included iron deficiency that was meant to offer an understanding of anemia and the supplementation modes that can be employed. Also, the term iron supplementation was searched to identify the journals with details concerning the IV and oral iron supplementation therapies. The other concept explored was Intravenous iron that aimed to present the various texts that explained the term giving its advantages and limitations. Additionally, the oral iron was looked up in the databases to generate ideas of its use and benefits in dealing with iron deficiency. The searches provided an extensive platform from which relevant papers were selected. However, the inclusion of other terms might have led to improved assessment of the two iron supplementation routes.

Literature Search Results.

            The searches in the various databases offered numerous citation numbers with several journal articles. The PMC, Cochrane, WHO, and EMBASE databases presented many texts that had diverse information concerning iron deficiency and the supplementation methods. Some had general details that did not address the IV and oral supplementation techniques and their differences. As a result, some adjustments were made to the initial searches to ensure that the citation returns obtained were of relevance to the question under evaluation. For instance, instead of looking up the term iron supplementation, the typed words were iron supplementation types of chronic and acute settings. The inclusion of the extra details served to give more appropriate and detailed articles regarding the subject…

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